The website for WELLBUTRIN SR is no longer available. WELLBUTRIN SR is approved for the treatment of depression in adults. To see the Complete Prescribing Information for WELLBUTRIN SR, click here.

The active ingredient in WELLBUTRIN SR is called bupropion. WELLBUTRIN SR is the bupropion formulation developed for twice daily dosing. Bupropion is also in other medicines such as ZYBAN® (bupropion HCl) Sustained-Release Tablets, WELLBUTRIN XL, and WELLBUTRIN® (bupropion HCl) Sustained-Release Tablets. If you are taking any form of bupropion you should not take any other medicine that contains bupropion.

WELLBUTRIN XL (bupropion HCl extended-release tablets) is the bupropion formulation developed for once-daily dosing. To learn more about once-daily WELLBUTRIN XL, click here to visit

Important Safety Information About WELLBUTRIN XL® (bupropion HCl extended-release tablets) and WELLBUTRIN SR® (bupropion HCl) Sustained-Release Tablets
WELLBUTRIN XL and WELLBUTRIN SR are not for everyone. There is a risk of seizure when taking WELLBUTRIN XL and WELLBUTRIN SR, so don't use if you've had a seizure or eating disorder, or if you abruptly stop using alcohol or sedatives. Don't take with MAOIs, or medicines that contain bupropion. When used with a nicotine patch or alone, there is a risk of increased blood pressure, sometimes severe. To reduce risk of serious side effects, tell your doctor if you have liver or kidney problems. Other side effects may include weight loss, dry mouth, nausea, difficulty sleeping, dizziness, or sore throat.

WELLBUTRIN XL and WELLBUTRIN SR are approved only for adults 18 years and over. In some children and teens, antidepressants increase suicidal thoughts or actions. Whether or not you are taking antidepressants, you or your family should call the doctor right away if you have worsening depression, thoughts of suicide, or sudden or severe changes in mood or behavior, especially at the beginning of treatment or after a change in dose (see Patient Information: What is important information I should know and share with my family about taking antidepressants?).
Complete Prescribing Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets).
Complete Prescribing Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets), is provided in Adobe's Portable Document Format (PDF). To view these documents you will need Adobe Acrobat Reader; if you do not have it, follow the link to download a copy.
If you are unable to or do not wish to download Acrobat Reader, but still wish to receive complete Prescribing Information, please click here.
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